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Volume 24, Number 4—April 2018
Research Letter

Chlamydia trachomatis in Cervical Lymph Node of Man with Lymphogranuloma Venereum, Croatia, 20141

Branimir GjurašinComments to Author , Snježana Židovec Lepej, Michelle J. Cole, Rachel Pitt, and Josip Begovac
Author affiliations: University Hospital for Infectious Diseases Dr. Fran Mihaljević, Zagreb, Croatia (B. Gjurašin, S.Ž. Lepej, J. Begovac); Public Health England, London, UK (M.J. Cole, R. Pitt); University of Zagreb School of Medicine, Zagreb (J. Begovac)

Main Article


Characteristics of 8 patients with lymphogranuloma venereum and cervical lymphadenopathy*

Reference Patient age, y/sex Clinical presentation Method of laboratory conformation Therapy/duration
Andrada et al. (4) 30/M Mouth ulcer, weight loss, cervical lymphadenopathy Serologic analysis Tetracycline/5 wk
Thorsteinsson et al. (3) 31/M Fever, supraclavicular, axillar, retroperitoneal, and cervical lymphadenopathy Serologic analysis Tetracycline/4 wk
Watson et al. (6) 19/F Sore throat, tonsillitis, arthritis, erythema nodosum, cervical lymphadenopathy Serologic analysis Phenoxymethylpenicillin, indomethacin, erythromycin†
Albay and Mathison (5) 18/F Fever, cervical lymphadenopathy Serologic analysis Ampicillin/sulbactam, doxycycline†
Tchernev et al. (8) 36/M Facial skin lesions, cervical and axillary lymphadenopathy NAAT: Chlamydia trachomatis DNA in skin lesions and serologic analysis Surgical excision of cervical lymph nodes; pentamidine and doxycycline/3 wk
Dosekun et al. (4) 32/M Sore throat, cervical lymphadenopathy, odynophagia, mouth ulcer, proctitis, cervical lymphadenopathy NAAT: LGV-specific DNA in pharyngeal swab specimen Amoxicillin/1 wk, doxycycline/1 wk
Dosekun et al. (4) 27/M Sore throat, cervical lymphadenopathy, odynophagia, mouth ulcer, proctitis, cervical lymphadenopathy NAAT: LGV-specific DNA in pharyngeal and rectal swab specimens Azithromycin/1 g, doxycycline/2 wk
This study 48/M Fever, cervical lymphadenopathy, proctitis NAAT: LGV-specific DNA in cervical lymph node sample obtained by fine-needle aspirate; serologic analysis Ceftriaxone/5 d, doxycycline/6 wk

*LGV, lymphogranuloma venereum; NAAT, nucleic acid amplification test.
†Duration of therapy not reported.

Main Article

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Main Article

1Results from this study were presented as a poster at the IDWEEK 2017 Conference, October 4–8, 2017, San Diego, CA, USA. Abstracts of the IDWEEK 2017 Conference have been published in a supplement issue of Open Forum Infectious Diseases (

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