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Volume 26, Number 10—October 2020
Research Letter

Using Virus Sequencing to Determine Source of SARS-CoV-2 Transmission for Healthcare Worker

Nasia SafdarComments to Author , Gage K. Moreno, Katarina M. Braun, Thomas C. Friedrich, and David H. O’Connor
Author affiliations: University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA (N. Safdar); William S. Middleton Memorial Veterans Hospital, Madison (N. Safdar); University of Wisconsin–Madison, Madison (G.K. Moreno, K.M. Braun, T.C. Friedrich, D.H. O’Connor)

Main Article

Figure 2

Severe acute respiratory syndrome coronavirus (SARS-CoV-2) consensus-level single-nucleotide variants (SNVs) from investigation of SARS-CoV-2 infection in HCW, Madison, Wisconsin, USA, 2020. The top alignment image depicts the SARS-CoV-2 genome for all persons evaluated in this investigation and highlights SNVs identified relative to the original SARS-CoV-2 reference isolate from Wuhan, China (GenBank accession no. MN908947.3). The table contains additional information about each of these SNVs.

Figure 2. Severe acute respiratory syndrome coronavirus (SARS-CoV-2) consensus-level single-nucleotide variants (SNVs) from investigation of SARS-CoV-2 infection in HCW, Madison, Wisconsin, USA, 2020. The top alignment image depicts the SARS-CoV-2 genome for all persons evaluated in this investigation and highlights SNVs identified relative to the original SARS-CoV-2 reference isolate from Wuhan, China (GenBank accession no. MN908947.3). The table contains additional information about each of these SNVs. Light blue shading indicates A2a clade-defining mutations. Dots indicate identity with reference sequence. Asterisk indicates a tyrosine-to–stop codon change. HCW, healthcare worker; HCW-F, HCW’s family member; ORF, open reading frame; UTR, untranslated region.

Main Article

Page created: August 05, 2020
Page updated: September 17, 2020
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