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Volume 26, Number 5—May 2020
Research

Effects of Air Pollution and Other Environmental Exposures on Estimates of Severe Influenza Illness, Washington, USA

Ranjani Somayaji, Moni B. Neradilek, Adam A. Szpiro, Kathryn H. Lofy, Michael L. Jackson, Christopher H. Goss, Jeffrey S. Duchin, Kathleen M. Neuzil, and Justin R. OrtizComments to Author 
Author affiliations: University of Calgary, Calgary, Alberta, Canada (R. Somayaji); University of Washington, Seattle, Washington, USA (R. Somayaji, A.A. Szpiro, C.H. Goss, J.S. Duchin); The Mountain-Whisper-Light Statistics, Seattle (M.B. Neradilek); Washington State Department of Health, Shoreline, Washington, USA (K.H. Lofy); Kaiser Permanente Washington Health Research Institute, Seattle (M.L. Jackson); Seattle & King County Public Health, Seattle (J.S. Duchin); University of Maryland School of Medicine, Baltimore, Maryland, USA (K.M. Neuzil, J.R. Ortiz)

Main Article

Table 1

Influenza-associated respiratory and circulatory hospitalizations by age group modeled with and without environmental covariates, October 2001–December 2012*

Model type and age group All influenza-attributable events All influenza-attributable events/100,000 person-years Influenza A–attributable events† Influenza A–attributable events/100,000 person-years† Influenza B–attributable events Influenza B– attributable events/100,000 person-years
Without environmental covariates‡
0–6 mo 254 118.7 342 159.9 −92 −42.9
7–23 mo 88 13.8 176 27.6 −90 −14.1
2–4 y 218 17.5 242 19.4 −25 −2.0
5–14 y 735 17.5 547 13.0 199 4.7
15–49 y 2,108 12.4 1,835 10.8 276 1.6
50–64 y 2,204 37.3 1,849 31.3 358 6.1
>65 y
5,376
157.0
2,782
81.3
2,609
76.2
With environmental covariates‡
0–6 mo 239 111.9 308 143.9 −71 −33.2
7–23 mo 87 13.6 174 27.2 −89 −13.9
2–4 y 215 17.2 240 19.3 −26 −2.1
5–14 y 741 17.6 571 13.6 181 4.3
15–49 y 1,885 11.1 1,618 9.5 270 1.6
50–64 y 2,064 34.9 1,667 28.2 401 6.8
>65 y 5,043 147.3 2,371 69.3 2,685 78.4

*The number of all influenza-attributable events is not equal to the sum of influenza A and influenza B events because the 2 types of influenza exposure are not independent and their attribution can overlap.
†We could not discern between influenza A(H3N2) and influenza A(H1N1) because of testing limitations over the study period.
‡Environmental covariates included daily averages of temperature, relative humidity, dew point, and particulate matter with a diameter <2.5 μm.

Main Article

Page created: April 16, 2020
Page updated: April 16, 2020
Page reviewed: April 16, 2020
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