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Volume 26, Number 6—June 2020
Dispatch

Increased Community-Associated Clostridioides difficile Infections in Quebec, Canada, 2008–20151

Veronica Zanichelli, Christophe Garenc, Jasmin Villeneuve, Danielle Moisan, Charles Frenette, Vivian Loo, Yves LongtinComments to Author , and Québec C.difficile Infection Surveillance Program (SPIN-CD)
Author affiliations: Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec, Canada (V. Zanichelli, Y. Longtin); Centre de Recherche du CHU de Quebec, Quebec City (C. Garenc); Institut National de Santé Publique du Québec, Quebec City, Quebec, Canada (C. Garenc, J. Villeneuve); CSSS Rivière-du-Loup, Rivière-du-Loup, Québec, Canada (D. Moisan); McGill University Health Centre, Montreal (C. Frenette, V. Loo, Y. Longtin)

Main Article

Table 2

Segmented regression of HA-CDI and CA-CDI in the province of Quebec, Canada, 2008–2015*

Rate 2008–2009 to 2010–2011
2011–2012 to 2014–2015
Overall trend before
the breakpoint, IRR (95% CI) p value Immediate change after the breakpoint, IRR (95% CI) p value Change in trend after the breakpoint, IRR (95% CI) p value
HA-CDI rate/10,000 patient-days 1.003 (1.001–1.005) 0.001 0.998 (0.945–1.053) 0.93 0.996 (0.994–0.998) 0.001
CA-CDI rate/100,000 population 1.007 (1.003–1.012) 0.002 0.95 (0.841–1.074) 0.41 0.997 (0.992–1.002) 0.30
Group difference 1.002 (0.997–1.007) 0.35 0.971 (0.851–1.107) 0.66 1.002 (0.996–1.008) 0.53

*Breakpoints were identified in April 2011. CA, community-acquired; HA, hospital-acquired; CDI, Clostridioides difficile infection; IRR, incidence rate ratio (calculated per 4-week period).

Main Article

1Preliminary results from this study were presented at the IDweek 2018 conference; 2018 Oct 3–7; San Francisco, California, USA (abstract no. 477).

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