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Volume 27, Number 12—December 2021
Research

Mammarenaviruses of Rodents, South Africa and Zimbabwe

Antoinette A. Grobbelaar, Jocelyn Jardine1, Felicity J. Burt2, Alasdair J. Shepherd, Susan P. Shepherd, Patricia A. Leman, Alan Kemp, Lawrence E.O. Braack3, Jacqueline WeyerComments to Author , Janusz T. Paweska, and Robert Swanepoel3
Author affiliations: National Institute for Communicable Diseases, Johannesburg, South Africa (A.A. Grobbelaar, J. Jardine, F.J. Burt, A.J. Shepherd, S.P. Shepherd, P.A. Leman, A. Kemp, J. Weyer, J.T. Paweska, R. Swanepoel); South African National Parks Board, Skukuza, South Africa (L.E.O. Braack).

Main Article

Table 4

Reactivity of selected mammarenavirus isolate-infected cell antigens in indirect immunofluorescence tests with monoclonal antibodies to Lassa fever and Mopeia viruses, South Africa and Zimbabwe*

Virus antigen
 Monoclonal antibody titer†
CDC 5254–6
Lassa N
 CDC 5293–4
Lassa N
 CDC 5273–8
Lassa N
 CDC 5285–6
Lassa G
 CDC 5329–1
Mopeia N
 NICD 4E9
Mopeia N
 NICD 3G9
Mopeia N
LCM Armstrong >12,800 – – 1,600 – – –
Lassa Josiah >12,800 >12,800 >12,800 3,200 – >12,800 –
Ippy DakAnB 188d >12,800 – – 3,200 3,200 >12,800 –
Mobala A11/3076 >12,800 – – 6,400 – >12,800 –
Mopeia AN 20410 >12,800 >12,800 – 400 >12,800 >12,800 >12,800
Mopeia SPU82/30/1 >12,800 >12,800 400 800 >12,800 >12,800 >12,800
Mopeia SPU84/491/73 >12,800 >12,800 400 200 >12,800 >12,800 >12,800
Bobomene SPU84/491/106 >12,800 >12,800 – 1,600 >12,800 >12,800 >12,800
Witsand SPU86/485 >12,800 >12,800 >12,800 – >12,800 >12,800 –
Omdraaivlei SPU86/415/2 >12,800 >12,800 >12,800 – >12,800 >12,800 –
Merino Walk SPU85/353 >12,800 – – – >12,800 – –

*G, antiglycoprotein; N, antinucleoprotein; –, none. †Antibody titers shown as reciprocals of serum dilution.

Main Article

1Current affiliation: EduVos, Midrand, South Africa.

2Current affiliation: University of the Free State, Bloemfontein, South Africa.

3Current affiliation: University of Pretoria, Pretoria, South Africa.

Page created: October 11, 2021
Page updated: November 19, 2021
Page reviewed: November 19, 2021
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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