Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 27, Number 12—December 2021

SARS-CoV-2–Specific Antibodies in Domestic Cats during First COVID-19 Wave, Europe

Claudia Schulz1, Byron Martina1, Monica Mirolo, Elisabeth Müller, Ruth Klein, Holger Volk, Herman Egberink, Mariana Gonzalez-Hernandez, Franziska Kaiser, Maren von Köckritz-Blickwede, and Albert OsterhausComments to Author 
Author affiliations: University of Veterinary Medicine Hannover, Hannover, Germany (C. Schulz, M. Mirolo, H. Volk, M. Gonzalez-Hernandez, F. Kaiser, M. von Köckritz-Blickwede, A. Osterhaus); Artemis One Health Research Foundation, Delft, the Netherlands (B. Martina, M. Mirolo); LABOklin, Kissingen, Germany (E. Müller, R. Klein); Utrecht University Faculty of Veterinary Medicine, Utrecht, the Netherlands (H. Egberink)

Main Article

Table 2

Comparison of diagnostic sensitivity and specificity of the RBD-ELISA and VNT in a study of SARS-CoV-2 seroprevalence among domestic cats during the first pandemic wave, Europe, April–August 2020*

Test results Value
RBD-ELISA sensitivity, % (95% CI) 90.6 (90.0–91.2)
RBD-ELISA specificity, % (95% CI) 99.8 (99.8–99.8)
No. positive (%; 95% CI), n = 2,160
RBD-ELISA and VNT 87 (4.0; 3.2–4.9)
RBD-ELISA only 92 (4.3; 3.5–5.2)
VNT only 96 (4.4; 3.6–5.4)

*A total of 5 samples were positive with RBD-ELISA and negative with VNT; 9 samples were positive with VNT but negative with RBD-ELISA. RBD-ELISA, receptor-binding domain–specific ELISA; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; VNT, virus neutralization test.

Main Article

1These authors contributed equally to this article.

Page created: September 01, 2021
Page updated: November 19, 2021
Page reviewed: November 19, 2021
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.