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Volume 27, Number 9—September 2021
Research

Genomic Epidemiology of Azithromycin-Nonsusceptible Neisseria gonorrhoeae, Argentina, 2005–2019

Ricardo Ariel Gianecini, Tomas Poklepovich, Daniel Golparian, Noelia Cuenca, Ezequiel Tuduri, Magnus Unemo, Josefina Campos, Patricia GalarzaComments to Author , and Gonococcal Antimicrobial Susceptibility Surveillance Programme—Argentina1
Author affiliations: Instituto Nacional de Enfermedades Infecciosas—Administración Nacional de Laboratorios e Institutos de Salud Dr. Carlos G. Malbrán, Buenos Aires, Argentina (R.A. Gianecini, T. Poklepovich, N. Cuenca, E. Tuduri, J. Campos, P. Galarza); World Health Organization Collaborating Centre for Gonorrhoea and Other STIs, Örebro University, Örebro, Sweden (D. Golparian, M. Unemo)

Main Article

Table 2

Antimicrobial susceptibility of 96 azithromycin-resistant Neisseria gonorrhoeae isolates, Argentina, January 2005–November 2019*

Antimicrobial drug Azithromycin MICs, μg/mL (no. isolates)
2–16 (91)
 >256 (5)
MIC50 MIC90 Range Resistance, % MIC Resistance, %
Ciprofloxacin 0.004 16 0.001–32 28.6 0.002–4 20
Tetracycline 1 2 0.125–4 25.3 0.5–2 20
Benzylpenicillin 1 2 0.25–8 14.3 0.5–1 0
Ceftriaxone 0.004 0.03 0.002–0.06 0 0.004–0.016 0
Cefixime 0.016 0.03 0.004–0.125 0 0.008–0.03 0
Spectinomycin 32 32 16–32 0 32 0
Gentamicin 8 8 4–16 0 8–16 0

*MIC50, MIC for 50% of isolates; MIC90, MIC for 90% of isolates.

Main Article

1Members of this group are listed at the end of the article.

Page created: July 01, 2021
Page updated: August 17, 2021
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