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Volume 28, Number 2—February 2022
Research

Effectiveness of mRNA BNT162b2 Vaccine 6 Months after Vaccination among Patients in Large Health Maintenance Organization, Israel

Jennifer KertesComments to Author , Sharon Baruch Gez, Yaki Saciuk, Lia Supino-Rosin, Naama Shamir Stein, Miri Mizrahi-Reuveni, and Anat E. Zohar
Author affiliation: Maccabi HealthCare Services, Tel Aviv‒Jaffa Israel

Main Article

Table 2

Mean antibody level by demographic and health variables and time from vaccination against coronavirus disease for population vaccinated against coronavirus disease, Maccabi Healthcare Services, Israel, January‒July 2021

Characteristic
 Days from vaccination to serologic test
 p value
7–29
 30–59
 60–89
 90–119
 120–150
 >150
Total population 2,457 1,845 946 827 500 1,820
Antibody levels
Mean 14,008 8,175 4,365 2,706 1,773 1,411 <0.001
SD 12,146 7,742 5,022 3,957 1,934 1,751
Median
 11,322
 6,080
 2,974
 1,683
 1,217
 1,217
Sex
No. male 1,075 676 354 269 105 295
Mean antibody level 12,278 6,837 3,799 2,633 1,695 1,309 <0.001
No. female 1,382 1,169 592 558 395 1,525
Mean antibody level
 15,354
 8,949
 4,703
 2,740
 1,794
 1,431
Age group, y
No. <18 32 40 14 6 0 0
Mean antibody level 29,781 15,348 9,971 9,421 <0.001
No. 18–44 677 469 262 201 142 448
Mean antibody level 18,522 9,866 5,621 3,271 2,006 1,479
No. 45–59 744 602 288 237 224 921
Mean antibody level 15,396 8,875 4,279 2,793 1,929 1,419
No. 60–74 821 599 302 264 99 430
Mean antibody level 9,999 6,280 3,684 2,670 1,478 1,256
No. >75 183 135 80 119 35 20
Mean antibody level
 6,892
 5,468
 2,147
 1,316
 668
 912
Socioeconomic status
No. low 553 278 143 113 59 135
Mean antibody level 15,994 10,048 4,481 4,056 2,443 1,625 <0.001
No. middle 1,088 827 414 392 259 932
Mean antibody level 13,989 8,473 4,739 2,523 1,695 1,468 <0.001
No. H\high 816 740 389 322 182 753
Mean antibody level
 12,687
 7,139
 3,924
 2,454
 1,667
 1,301
 <0.001
Underlying conditions
Heart disease
No. patients 206 165 79 75 25 55
Mean antibody level 7,341 4,307 2,520 2,455 690 1,575 <0.001
Diabetes
No. patients 377 245 121 123 57 130
Mean antibody level 8,624 6,647 2,742 2,189 843 1,401 <0.001
Hypertension
No. patients 803 572 274 290 133 363
Mean antibody level 9,930 6,624 3,032 2,118 1,341 1,409 <0.001
Chronic kidney disease
No. patients 248 163 81 88 45 55
Mean antibody level 6,756 4,331 2,614 2,339 887 1,910 <0.001
Immunosuppressive disorder
No. patients 307 280 156 126 57 58
Mean antibody level 6,824 4,371 2,336 1,500 1,033 1,813 <0.001

Main Article

Page created: November 16, 2021
Page updated: January 22, 2022
Page reviewed: January 22, 2022
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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