Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 29, Number 5—May 2023
Dispatch

Poor Prognosis for Puumala Virus Infections Predicted by Lymphopenia and Dyspnea

Stefan Hatzl, Florian Posch, Marina Linhofer, Stephan Aberle, Ines Zollner-Schwetz, Florian Krammer, and Robert KrauseComments to Author 
Author affiliations: Medical University of Graz, Graz, Austria (S. Hatzl, F. Posch, M. Linhofer, I. Zollner-Schwetz, R. Krause); Medical University of Vienna, Vienna, Austria (S. Aberle); Icahn School of Medicine at Mount Sinai, New York, New York, USA (F. Krammer)

Main Article

Figure

Poor prognosis for PUUV infections predicted by lymphopenia and dyspnea. A) Box plot showing difference in ALC between patients who had a mild clinical course and those who had a severe clinical course, showing that those with lower ALCs were more likely to have severe illness. Horizontal lines within indicate medians, top lines are maximum values, bottom lines are minimum values, and error bars indicate 25th‒75th percentiles. B) Risk for severe course of PUUV infection according to the calculated ALC cutoff of 0.9 g/L, showing that lower ALC predicted increased risk for severe illness. C) Risk for developing severe PUUV infection according to dyspnea at first medical contact, showing that dyspnea predicted increased risk for severe illness. ALC, absolute lymphocyte count; G, giga; PUUV, Puumala virus.

Figure. Poor prognosis for PUUV infections predicted by lymphopenia and dyspnea. A) Box plot showing difference in ALC between patients who had a mild clinical course and those who had a severe clinical course, showing that those with lower ALCs were more likely to have severe illness. Horizontal lines within indicate medians, top lines are maximum values, bottom lines are minimum values, and error bars indicate 25th‒75th percentiles. B) Risk for severe course of PUUV infection according to the calculated ALC cutoff of 0.9 g/L, showing that lower ALC predicted increased risk for severe illness. C) Risk for developing severe PUUV infection according to dyspnea at first medical contact, showing that dyspnea predicted increased risk for severe illness. ALC, absolute lymphocyte count; G, giga; PUUV, Puumala virus.

Main Article

Page created: February 17, 2023
Page updated: April 25, 2023
Page reviewed: April 25, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external