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Volume 29, Number 9—September 2023
Dispatch

Prevalence of Asymptomatic Mpox among Men Who Have Sex with Men, Japan, January–March 2023

Daisuke Mizushima1Comments to Author , Yui Shintani1, Misao Takano, Daisuke Shiojiri, Naokatsu Ando, Takahiro Aoki, Koji Watanabe, Takato Nakamoto, Hiroyuki Gatanaga, and Shinichi Oka
Author affiliations: National Center for Global Health and Medicine, Tokyo, Japan (D. Mizushima, Y. Shintani, M. Takano, D. Shiojiri, N. Ando, T. Aoki, K. Watanabe, T. Nakamoto, H. Gatanaga, S. Oka); Personal Health Clinic, Tokyo (D. Shiojiri); Kumamoto University, Kumamoto, Japan (H. Gatanaga, S. Oka)

Main Article

Table

Characteristics among cases in a study of prevalence of asymptomatic mpox among men who have sex with men, Japan, January–March 2023*

Case no. Classification HIV status Sample type Ct value Timeframe, d
 Symptoms
Sexual activity to diagnosis Sexual activity to symptom onset Negative test to symptom onset Symptom onset to diagnosis Negative test to diagnosis
1 Asymptomatic On PrEP Anorectal swab 21.2 10 NA NA NA NA NA
2 Asymptomatic HIV Pooled† 20.8 29 NA NA NA NA NA
3 Asymptomatic On PrEP Pooled† 28.4 ND NA NA NA NA NA
4 Symptomatic‡ HIV Pooled† 28.8 8 11 NA NA NA Skin lesions
5 Symptomatic§ On PrEP Pooled† 31.0 48 8 NA NA NA Fever and pharyngitis
6 Symptomatic¶ HIV Skin lesion swab ND 22 15 32 7 39 Skin lesions
7 Symptomatic¶ On PrEP Skin lesion swab ND 23 18 48 5 53 Skin lesions, fever, lymphadenopathy, and pharyngitis
8 Symptomatic¶ On PrEP Skin lesion swab ND 18 9 13 9 22 Skin lesions, fever, lymphadenopathy, and pharyngitis
9 Symptomatic¶
 HIV Skin lesion swab ND 8 4 53 4 57 Skin lesions and lymphadenopathy

*Ct, cycle threshold; NA, not applicable; ND, no data; PrEP, preexposure prophylaxis. †Samples consisted of anorectal swabs, initial stream urine, and gargle rinse. ‡Initially asymptomatic but had symptoms develop during study. §Initially asymptomatic, but patient later reported previous self-resolving symptoms. ¶Initially tested negative but had symptoms develop during study.

Main Article

1These authors contributed equally to this article.

Page created: July 21, 2023
Page updated: August 20, 2023
Page reviewed: August 20, 2023
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