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Volume 30, Number 5—May 2024
Research

Antimicrobial Resistance as Risk Factor for Recurrent Bacteremia after Staphylococcus aureus, Escherichia coli, or Klebsiella spp. Community-Onset Bacteremia

Salam AbbaraComments to Author , Didier Guillemot, David R.M. Smith, Salma El Oualydy, Maeva Kos, Cécile Poret, Stéphane Breant, Christian Brun-Buisson, and Laurence Watier
Author affiliations: Institut National de la Santé et de la Recherche Médicale, Montigny–Le-Bretonneux, France (S. Abbara, D. Guillemot, C. Brun-Buisson, L. Watier); Versailles Saint Quentin en Yvelines University, Montigny–Le-Bretonneux (S. Abbara, D. Guillemot, C. Brun-Buisson, L. Watier); Institut Pasteur, Paris, France (S. Abbara, D. Guillemot, C. Brun-Buisson, L. Watier); Paris–Cité University, Paris (S. Abbara, D. Guillemot, C. Brun-Buisson, L. Watier); Paris–Saclay University, Le Kremlin–Bicêtre, France (D. Guillemot); Assistance Publique–Hôpitaux de Paris, Paris (D. Guillemot, C. Poret, S. Breant); University of Oxford, Oxford, UK (D.R.M. Smith); Plateforme de Données de Santé, Paris (S. El Oualydy, M. Kos)

Main Article

Table 3

Subdistribution HRs for relationship between each bacteria-resistance pair and recurrence of bacteremia at 1 year in final multivariable model, by reference, in study of community-onset bacteremia attributable to Staphylococcus aureus, Escherichia coli, or Klebsiella spp., Assistance Publique–Hôpitaux de Paris university hospital group, Paris, France, 2017–2019*

Bacteria resistance HR (95% CI)
Referent MSSA Referent 3GC-susceptible E. coli Referent 3GC-susceptible Klebsiella spp.
MSSA Referent 0.86 (0.60–1.23) 0.71 (0.45–1.11)
MRSA 0.79 (0.29–2.19) 0.68 (0.25–1.86) 0.56 (0.20–1.59)
3GC-susceptible E. coli 1.16 (0.81–1.66) Referent 0.82 (0.56–1.20)
3GC-resistant E. coli 2.35 (1.50–3.68) 2.02 (1.41–2.91) 1.66 (1.04–2.66)
3GC-susceptible Klebsiella spp. 1.41 (0.91–2.21) 1.22 (0.83–1.78) Referent
3GC-resistant Klebsiella spp. 3.91 (2.32–6.59) 3.37 (2.10–5.41) 2.77 (1.60–4.79)

*Results are adjusted on all the variables described in Table 2. 3GC, third-generation cephalosporin; HR, subdistribution hazard ratio; MRSA, methicillin-resistant S. aureus; MSSA, methicillin-susceptible S. aureus.

Main Article

Page created: March 28, 2024
Page updated: April 23, 2024
Page reviewed: April 23, 2024
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