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Volume 7, Number 5—October 2001
Synopsis

Cost-Effectiveness of a Potential Vaccine for Coccidioides immitis

Amber E. Barnato*Comments to Author , Gillian D. Sanders†, and Douglas K. Owens†‡
Author affiliations: *University of Pittsburgh, Pittsburgh, Pennsylvania, USA; †Stanford University, Stanford, California, USA; ‡VA Palo Alto Health Care System, Palo Alto, California, USA

Main Article

Figure 1

Areas in the United States endemic for Coccidioides immitis. Cross-hatching indicates the heavily disease-endemic area; single hatching indicates the moderately disease-endemic area. Reprinted with the author's permission from Kirkland (1).

Figure 1. . Areas in the United States endemic for Coccidioides immitis. Cross-hatching indicates the heavily disease-endemic area; single hatching indicates the moderately disease-endemic area. Reprinted with the author's permission from Kirkland (1).

Main Article

References
  1. Kirkland  TN, Fierer  J. Coccidioidomycosis: a reemerging infectious disease. Emerg Infect Dis. 1996;2:1929. DOIPubMedGoogle Scholar
  2. Maddy  KT. The geographic distribution of Coccidioides immitis and possible ecologic implications. Ariz Med. 1958;15:178.PubMedGoogle Scholar
  3. Population estimates. Washington: U.S. Census Bureau; 1999.
  4. Flynn  NM, Hoeprich  PD, Kawachi  MM, Lee  KK, Lawrence  RM, Goldstein  E, An unusual outbreak of windborne coccidioidomycosis. N Engl J Med. 1979;301:35861. DOIPubMedGoogle Scholar
  5. Schneider  E, Hajjeh  RA, Spiegel  RA, Jibson  RW, Harp  EL, Marshall  GA, A coccidioidomycosis outbreak following the Northridge, Calif, earthquake. JAMA. 1997;277:9048. DOIPubMedGoogle Scholar
  6. Johnson  WM. Occupational factors in coccidioidomycosis. J Occup Med. 1981;23:36774.PubMedGoogle Scholar
  7. Werner  SB, Pappagianis  D, Heindl  I, Mickel  A. An epidemic of coccidioidomycosis among archeology students in northern California. N Engl J Med. 1972;286:50712. DOIPubMedGoogle Scholar
  8. Standaert  SM, Schaffner  W, Galgiani  JN, Pinner  RW, Kaufman  L, Durry  E, Coccidioidomycosis among visitors to a Coccidioides immitis-endemic area: an outbreak in a military reserve unit. J Infect Dis. 1995;171:16725. DOIPubMedGoogle Scholar
  9. Hooper  R, Poppell  G, Curley  R, Husted  S, Schillaci  R. Coccidioidomycosis among military personnel in Southern California. Mil Med. 1980;145:6203.PubMedGoogle Scholar
  10. Centers for Disease Control and Prevention. Coccidioidomycosis--California, 1991-1993. MMWR Morb Mortal Wkly Rep. 1994;43:4213.PubMedGoogle Scholar
  11. Centers for Disease Control and Prevention. Coccidioidomycosis--Arizona, 1990-1995. MMWR Morb Mortal Wkly Rep. 1996;45:106973.PubMedGoogle Scholar
  12. Caldwell  J, Welch  G, Johnson  RH, Einstein  HE. The economic impact of coccidioidomycosis in Kern County, California, 1991 to 1993. In: Einstein HE, Catanzaro A, editors. Coccidioidomycosis: proceedings of the 5th international conference. Washington: National Foundation for Infectious Diseases; 1994: p. 88-97.
  13. Pappagianis  D. Evaluation of the protective efficacy of the killed Coccidioides immitis spherule vaccine in humans. Am Rev Respir Dis. 1993;148:65660. DOIPubMedGoogle Scholar
  14. Stratton  KR, Durch  JS, Lawrence  RS. Vaccines for the 21st century: a tool for decision making. Washington: Division of Health Promotion and Disease Prevention, Institute of Medicine; 1999.
  15. Gold  M, Franks  P, McCoy  K, Fryback  DG. Toward consistency in cost-utility analyses: using national measures to create condition-specific values. Med Care. 1998;36:77892. DOIPubMedGoogle Scholar
  16. Beck  JR, Sauker  SG. The Markov process in medical prognosis. Med Decis Making. 1983;3:41958. DOIPubMedGoogle Scholar
  17. Sonnenberg  FA, Beck  JR. Markov models in medical decision making: a practical guide. Med Decis Making. 1993;13:32238. DOIPubMedGoogle Scholar
  18. Centers for Disease Control and Prevention, National Center for Health Statistics (NCHS). Monthly vital statistics report: annual summary of births, marriages, divorces, and deaths: United States. Hyattsville (MD): NCHS; 1995.
  19. Centers for Disease Control and Prevention. Coccidioidomycosis--United States, 1991-1992. MMWR Morb Mortal Wkly Rep. 1993;42:214.PubMedGoogle Scholar
  20. Smith  CE, Beard  RR. Varieties of coccidioidal infection in relation to the epidemiology and control of diseases. Am J Public Health. 1946;36:1394402. DOIGoogle Scholar
  21. Einstein  HE, Johnson  RH. Coccidioidomycosis: new aspects of epidemiology and therapy. Clin Infect Dis. 1993;16:34954. DOIPubMedGoogle Scholar
  22. Arsura  E, Caldwell  J, Johnson  R, Einstein  H, Welch  G, Talbot  R, Coccidioidomycosis epidemic of 1991: epidemiologic features. In: Einstein HE, Catanzaro A, editors. 5th International Conference on Coccidioidomycosis. Stanford University, Aug 24-27, 1994. Bethesda (MD): National Foundation for Infectious Diseases; 1996. p. 98-107.
  23. Galgiani  JN. Coccidioidomycosis: a regional disease of national importance; rethinking approaches for control. Ann Intern Med. 1999;130:293300.PubMedGoogle Scholar
  24. Assad  S. Over a decade of experience with a yeast recombinant hepatitis B vaccine. Vaccine. 1999;18:5767. DOIPubMedGoogle Scholar
  25. Lebowitz  MD, Johnson  WM, Kaltenborn  W. Coccidioidin skin test reactivity and cross-reactivity with histoplasmin in a Tucson population. In: Ajello L, editor. Coccidioidomycosis: current clinical and diagnostic status. Vol 1. Miami: Symposia Specialists; 1977. p. 45-61.
  26. Dodge  RR, Lebowitz  MD, Barbee  R, Burrows  B. Estimates of C. immitis infection by skin test reactivity in an endemic community. Am J Public Health. 1985;75:8635. DOIPubMedGoogle Scholar
  27. Geller  RD, Maynard  JE, Jones  V. Coccidioidin sensitivity among Southwestern American Indians. Am Rev Respir Dis. 1973;107:3012.PubMedGoogle Scholar
  28. Stevens  DA, Levine  HB, Deresinski  SC, Ten Eyck  DR, Restrepo  MA. Epidemiological and clinical skin testing studies with spherulin. In: Ajello L, editor. Coccidioidomycosis: current clinical and diagnostic status. Vol 1. Miami: Symposia Specialists; 1977. p. 107-14.
  29. Levine  HB, Gonzalez-Ochoa  A, Ten Eyck  DR. Dermal sensitivity to Coccidioides immitis. a comparison of responses elicited in man by spherulin and coccidioidin. Am Rev Respir Dis. 1973;107:37986.PubMedGoogle Scholar
  30. Levine  HB, Restrepon  A, Eyck  DR, Stevens  DA. Spherulin and coccidioidin: cross-reactions in dermal sensitivity to histoplasmin and paracoccidioidin. Am J Epidemiol. 1975;101:5126.PubMedGoogle Scholar
  31. Healthcare Cost and Utilization Project: Nationwide Inpatient Sample. Rockville (MD): Agency for Healthcare Research and Quality; 1996.
  32. Revised 2000 National physician fee schedule. Baltimore: Health Care Financing Administration; 2000.
  33. Manton  KG, Etallard  E. Chapter 6: Program payment and utilization trends for Medicare beneficiaries with disabilities. In: Wiener JM, Clauser SB, Kenner DL, editors. Persons with disabilities. Washington: The Brookings Institution; 1995. p. 117-62.
  34. Klotz  AL, Biddle  M. Coccidioidin skin test survey of San Fernando Valley State college students over a five year period. In: Ajello L, editor. The Second Symposium on Coccidioidomycosis. Phoenix (AZ): University of Arizona Press; 1965. p. 251-3.
  35. Sisk  JE, Moskowitz  AJ, Whang  W, Lin  JD, Fedson  DS, McBean  AM, Cost-effectiveness of vaccination against pneumococcal bacteremia among elderly people. JAMA. 1997;278:13339. DOIPubMedGoogle Scholar
  36. Wright  JC, Weinstein  MC. Gains in life expectancy from medical interventions--standardizing data on outcomes. N Engl J Med. 1998;339:3806. DOIPubMedGoogle Scholar
  37. Arsura  EL. The association of age and mortality in coccidioidomycosis [letter]. J Am Geriatr Soc. 1997;45:5323.PubMedGoogle Scholar
  38. Lang  J, Wood  SW. Development of orphan vaccines: an industry perspective. Emerg Infect Dis. 1999;5:74956. DOIPubMedGoogle Scholar
  39. Garber  AM. Advances in cost-effectiveness analysis of health interventions. In: Culyer A, Newhouse J, editors. Handbook of health economics. Vol. 1. New York: Elsevier Science B; 2000. p. 182-219.
  40. Population estimates. Washington: U.S. Census Bureau; 1999.
  41. Sarosi  GA, Parker  JD, Doto  IL, Tosh  FE. Chronic pulmonary coccidioidomycosis. N Engl J Med. 1970;283:3259. DOIPubMedGoogle Scholar
  42. Bayer  AS. Fungal pneumonias: pulmonary coccidioidal syndromes (Part 2). Miliary, nodular, and cavitary pulmonary coccidioidomycosis; chemotherapeutic and surgical considerations. Chest. 1981;79:68691. DOIPubMedGoogle Scholar
  43. Bayer  AS. Fungal pneumonias; pulmonary coccidioidal syndromes (Part 1). Primary and progressive primary coccidioidal pneumonias--diagnostic, therapeutic, and prognostic considerations. Chest. 1981;79:57583. DOIPubMedGoogle Scholar
  44. Einstein  HE, Johnson  RH. Coccidioidomycosis: new aspects of epidemiology and therapy. Clin Infect Dis. 1993;16:34954. DOIPubMedGoogle Scholar
  45. Galgiani  JN. Coccidioidomycosis. In: Remington JS, Swartz MN, editors. Curr Clin Top Infect Dis 1997:188-204.
  46. Smith  CE, Beard  RR. Varieties of coccidioidal infection in relation to the epidemiology and control of diseases. Am J Public Health. 1946;36:1394402. DOIGoogle Scholar
  47. Smith  CE. Coccidioidomycosis. In: Hayes SB, Coate JB, editors. Preventive medicine in World War II. Vol. 4. Washington: Department of the Army; 1958. p. 285.
  48. Centers for Disease Control and Prevention. Coccidioidomycosis--Arizona, 1990-1995. MMWR Morb Mortal Wkly Rep. 1996;45:106973.PubMedGoogle Scholar
  49. Arsura  E, Caldwell  J, Johnson  R, Einstsein  H, Welch  G, Talbot  R, Coccidioidomycosis epidemic of 1991: epidemiologic features. In: Einstein HE, Catanzaro A, editors. 5th International Conference on Coccidioidomycosis. Stanford (CA): National Foundation for Infectious Diseases; 1994. p. 98-107.
  50. Caldwell  J, Welch  G, Johnson  RH, Einstein  HE. The economic impact of coccidioidomycosis in Kern County, California, 1991 to 1993. In: Einstein HE, Catanzaro A, editors. Coccidioidomycosis: Proceedings of the 5th International Conference. Washington: National Foundation for Infectious Diseases; 1994. p. 88-97.
  51. Gifford  M, Buss  W, Douds  R. Annual Report of the Kern County Health Department for the fiscal year July 1, 1936 to June 30, 1937. Bakersfield (CA): The Department; 1937.
  52. Willett  F, Weiss  A. Coccidioidomycosis in Southern California: Report of a new endemic area with a review of 100 cases. Ann Intern Med. 1945;23:34975.
  53. McCracken  BE. (Surgeon's Office 6th Army). Final report of coccidioidomycosis research project at Camp Roberts, California, 1 Sept 1952-15 Oct 1953.
  54. Pappagianis  D, Einstein  H. Tempest from Tehachapi takes toll or Coccidioides conveyed aloft and afar. West J Med. 1978;129:52730.PubMedGoogle Scholar
  55. Flynn  NM, Hoeprich  PD, Kawachi  MM, Lee  KK, Lawrence  RM, Goldstein  E, An unusual outbreak of windborne coccidioidomycosis. N Engl J Med. 1979;301:35861. DOIPubMedGoogle Scholar
  56. Cody  S, Emergy  K, Werner  SB, Talbot  R, Hajjeh  R, Reingold  A, Population-based surveillance for coccidioidomycosis in Kern County, CA, 1995 [poster #P-16.2]. International Conference on Emerging Infectious Diseases. Atlanta (GA), Mar 8-11, 1998.
  57. Pappagianis  D, Lindsay  S, Beall  S, Williams  P. Ethnic background and the clinical course of coccidioidomycosis [letter]. Am Rev Respir Dis. 1979;120:95961.PubMedGoogle Scholar
  58. Sievers  ML. Disease patterns among southwestern Indians. Public Health Rep. 1966;81:107583. DOIPubMedGoogle Scholar
  59. Sievers  ML. Disseminated coccidioidomycosis among southwestern American Indians. Am Rev Respir Dis. 1974;109:60212.PubMedGoogle Scholar
  60. Sievers  ML. Prognostic factors in disseminated coccidioidomycosis among Southwestern American Indians. In: Ajello L, editor. Coccidioidomycosis: Current clinical and dignostic satus. Vol. 1. Miami: Symposia Specialists; 1977. p. 63-78.
  61. Sievers  M. Racial susceptibility to coccidioidomycosis [letter]. N Engl J Med. 1980;302:589. DOIPubMedGoogle Scholar
  62. Sievers  ML, Fisher  JR. Decreasing incidence of disseminated coccidioidomycosis among Piman and San Carlos Apache Indians. A probable environmental basis. Chest. 1982;82:45560. DOIPubMedGoogle Scholar
  63. Sievers  ML, Nelson  RG, Bennett  PH. Adverse mortality experience of a Southwestern American Indian community: overall death rates and underlying causes of death in Pima Indians. J Clin Epidemiol. 1990;43:123142. DOIPubMedGoogle Scholar
  64. Louie  L, Ng  S, Hajjeh  R, Johnson  R, Vujia  D, Werner  SB, Influence of host genetics on the severity of coccidioidomycosis. Emerg Infect Dis. 1999;5:67280. DOIPubMedGoogle Scholar
  65. Jinadu  BA. Valley Fever task force: report on the control of Coccidioides immitis. Bakersfield (CA): Kern County Health Department; Aug 1995.
  66. Drutz  DJ. Urban coccidioidomycosis and histoplasmosis: Sacramento and Indianapolis [editorial]. N Engl J Med. 1979;301:3812. DOIPubMedGoogle Scholar
  67. Johnson  RH, Caldwell  JW, Welch  G, Einstein  HE. The great coccidioidomycosis epidemic: clinical features. In: Einstein HE, Catanzaro A, editors. Coccidioidomycosis: 5th International Conference. Stanford (CA): National Foundation for Infectious Diseases; 1994. p. 77-87.
  68. Einstein  H, Johnson  R, Caldwell  J, Antonescu  A, Reddy  V. Coccidioidomycosis and pregnancy: The Kern County experience. In: Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy; Sept 17-20, 1995. Washington: American Society for Microbiology; 1995. p. 324.
  69. McCoy  MJ, Ellenberg  JF, Killam  AP. Coccidioidomycosis complicating pregnancy. Am J Obstet Gynecol. 1980;137:73940.PubMedGoogle Scholar
  70. Smale  LE, Waechter  KG. Dissemination of coccidioidomycosis in pregnancy. Am J Obstet Gynecol. 1970;107:35661.PubMedGoogle Scholar
  71. Peterson  CM, Johnson  SL, Kelly  JV, Kelly  PC. Coccidioidal meningitis and pregnancy: a case report. Obstet Gynecol. 1989;73:8356.PubMedGoogle Scholar
  72. Wack  EE, Ampel  NM, Galgiani  JN, Bronnimann  DA. Coccidioidomycosis during pregnancy. An analysis of ten cases among 47,120 pregnancies. Chest. 1988;94:3769. DOIPubMedGoogle Scholar
  73. Peterson  CM, Schuppert  K, Kelly  PC, Pappagianis  D. Coccidioidomycosis and pregnancy. Obstet Gynecol Surv. 1993;48:14956. DOIPubMedGoogle Scholar
  74. VanBergen  WS, Fleury  FJ, Cheatle  EL. Fatal maternal disseminated coccidioidomycosis in a nonendemic area. Am J Obstet Gynecol. 1976;124:6613.PubMedGoogle Scholar
  75. Healthcare Cost and Utilization Project: Nationwide Inpatient Sample. Rockville (MD): Agency for Healthcare Research and Quality; 1996.
  76. U.S. Preventive Services Task Force. Guide to clinical preventive services. 2nd ed. Alexandria (VA): International Medical Publishing; 1996.
  77. Szmuness  W, Stevens  CE, Harley  EJ, Zang  EA, Oleszko  WR, William  DC, Hepatitis B vaccine: demonstration of efficacy in a controlled clinical trial in a high risk population in the United States. N Engl J Med. 1980;303:83341. DOIPubMedGoogle Scholar
  78. Stevens  DA, Levine  HB, Deresinski  SC, Ten Eyck  DR, Restrepo  MA. Epidemiological and clinical skin testing studies with spherulin. In: Ajello L, editor. Coccidioidomycosis: Current clinical and diagnostic status. Vol. 1. Miami: Symposia Specialists; 1977. p. 107-14.
  79. Lebowitz  MD, Johnson  WM, Kaltenborn  W. Coccidioidin skin test reactivity and cross-reactivity with histoplasmin in a Tucson population. In: Ajello L, editor. Coccidioidomycosis: Current clinical and diagnostic status. Vol. 1. Miami: Symposia Specialists; 1977. p. 45-61.
  80. Dodge  RR, Lebowitz  MD, Barbee  R, Burrows  B. Estimates of C. immitis infection by skin test reactivity in an endemic community. Am J Public Health. 1985;75:8635. DOIPubMedGoogle Scholar
  81. Levine  HB, Gonzalez-Ochoa  A, Ten Eyck  DR. Dermal sensitivity to Coccidioides immitis. A comparison of responses elicited in man by spherulin and coccidioidin. Am Rev Respir Dis. 1973;107:37986.PubMedGoogle Scholar
  82. Levine  HB, Restrepon  A, Eyck  DR, Stevens  DA. Spherulin and coccidioidin: cross-reactions in dermal sensitivity to histoplasmin and paracoccidioidin. Am J Epidemiol. 1975;101:5126.PubMedGoogle Scholar
  83. Gifford  M, Buss  W, Douds  R. Annual report of the Kern County Health Department for the fiscal year July 1, 1936 to June 30, 1937.
  84. Edwards  PQ, Palmer  CE. Prevalence of sensitivity to coccidioidin, with special reference to specific and nonspecific reactions to coccidioidin and to histoplasmin. Dis Chest. 1957;31:3560.PubMedGoogle Scholar
  85. Hugenhotz  PG. Skin test survey at Williams Air Force Base, Arizona. In: Symposium on Coccidioidomycosis, Phoenix, AZ. Washington: U.S. Government Printing Office; 1957.
  86. Maddy  KT. The geographic distribution of Coccidioides immitis and possible ecologic implications. Ariz Med. 1958;15:178.PubMedGoogle Scholar
  87. Klotz  AL, Biddle  M. Coccidioidin skin test survey of San Fernando Valley State college students over a five year period. In: The Second Symposium on Coccidioidomycosis. Phoenix (AZ): University of Arizona Press; 1965.
  88. Doto  I. Coccidioidin, histoplasmin, and tuberculin sensitivity among school children in Maricopa Co., Arizona. Am J Epidemiol. 1972;95:464.PubMedGoogle Scholar
  89. Catanzaro  A. Coccidioidin sensitivity in San Diego schools. Sabouraudia. 1979;17:859. DOIPubMedGoogle Scholar
  90. Fredrich  BE. A skin test survey of valley fever in Tijuana, Mexico. Soc Sci Med. 1989;29:121727. DOIPubMedGoogle Scholar
  91. Larwood  T. Coccidioidin skin testing in Kern County, California: decrease in infection rate over 58 years. Clin Infect Dis. 2000;30:6123. DOIPubMedGoogle Scholar
  92. Smith  CE, Beard  RR. Varieties of coccidiodal infection in relation to the epidemiology and control of diseases. Am J Public Health. 1946;36:1394402. DOIGoogle Scholar
  93. Bayer  AS. Fungal pneumonias; pulmonary coccidioidal syndromes (Part 1). Primary and progressive primary coccidioidal pneumonias --diagnostic, therapeutic, and prognostic considerations. Chest. 1981;79:57583. DOIPubMedGoogle Scholar
  94. Arsura  E, Caldwell  J, Johnson  R, Einstein  H, Welch  G, Talbot  R, Coccidioidomycosis epidemic of 1991: epidemiologic features. In: 5th International Conference on Coccidioidomycosis. Stanford (CA) University: National Foundation for Infectious Diseases; 1994.
  95. Arsura  EL. The association of age and mortality in coccidioidomycosis letter. J Am Geriatr Soc. 1997;45:5323.PubMedGoogle Scholar
  96. Johnson  RH, Caldwell  JW, Welch  G, Einstein  HE. The great coccidioidomycosis epidemic: clinical features. In: Coccidioidomycosis: 5th International Conference. Stanford (CA) University: National Foundation for Infectious Diseases; 1994.
  97. Sarosi  GA, Parker  JD, Doto  IL, Tosh  FE. Chronic pulmonary coccidioidomycosis. N Engl J Med. 1970;283:3259. DOIPubMedGoogle Scholar
  98. Bayer  AS. Fungal pneumonias: pulmonary coccidioidal syndromes (Part 2). Miliary, nodular, and cavitary pulmonary coccidioidomycosis; chemotherapeutic and surgical considerations. Chest. 1981;79:68691. DOIPubMedGoogle Scholar
  99. Einstein  HE, Johnson  RH. Coccidioidomycosis: new aspects of epidemiology and therapy. Clin Infect Dis. 1993;16:34954. DOIPubMedGoogle Scholar
  100. Galgiani  JN. Coccidioidomycosis. In: Remington JS, Swartz MN, editors. Curr Clin Top Infect Dis 1997:188-204.
  101. Vincent  T, Galgiani John  N, Huppert  M, Salkin  D. The natural history of coccidioidal meningitis: VA-Armed Forces Cooperative Studies, 1955-1958. Clin Infect Dis. 1993;16:24754. DOIPubMedGoogle Scholar
  102. Bouza  E, Dreyer  JS, Hewitt  WL, Meyer  RD. Coccidioidal meningitis. An analysis of thirty-one cases and review of the literature. Medicine. 1981;60:13972.PubMedGoogle Scholar
  103. Galgiani  JN, Catanzaro  A, Cloud  GA, Higgs  J, Friedman  BA, Larsen  RA, Fluconazole therapy for coccidioidal meningitis. The NIAID-Mycoses Study Group. Ann Intern Med. 1993;119:2835.PubMedGoogle Scholar
  104. Perez  JA Jr, Johnson  RH, Caldwell  JW, Arsura  EL, Nemecheck  P. Fluconazole therapy in coccidioidal meningitis maintained with intrathecal amphotericin B. Arch Intern Med. 1995;155:16658. DOIPubMedGoogle Scholar
  105. Tucker  RM, Denning  DW, Dupont  B, Stevens  DA. Itraconazole therapy for chronic coccidioidal meningitis. Ann Intern Med. 1990;112:10812.PubMedGoogle Scholar
  106. Catanzaro  A, Galgiani  JN, Levine  BE, Sharkey-Mathis  PK, Fierer  J, Stevens  DA, Fluconazole in the treatment of chronic pulmonary and nonmeningeal disseminated coccidioidomycosis. NIAID Mycoses Study Group. Am J Med. 1995;98:24956. DOIPubMedGoogle Scholar
  107. Galgiani  JN, Catanzaro  A, Cloud  GA, Johnson  RH, Williams  PL, Mirels  LF, Comparison of oral fluconazole and itraconazole for progressive, nonmeningeal coccidioidomycosis. A randomized, double-blind trial. Mycoses Study Group. Ann Intern Med. 2000;133:67686.PubMedGoogle Scholar
  108. Graybill  JR, Stevens  DA, Galgiani  JN, Dismukes  WE, Cloud  GA. Itraconazole treatment of coccidioidomycosis. NAIAD Mycoses Study Group. Am J Med. 1990;89:28290. DOIPubMedGoogle Scholar
  109. Oldfield  EC III, Bone  WD, Martin  CR, Gray  GC, Olson  P, Schillaci  RF. Prediction of relapse after treatment of coccidioidomycosis. Clin Infect Dis. 1997;25:120510. DOIPubMedGoogle Scholar
  110. Niu  MT, Rhodes  P, Salive  M, Liveley  T, Davis  DM, Black  S, Comparative safety data of two recombinant hepatitis B vaccines in children: data from the Vaccine Adverse Event Reporting System (VAERS) and Vaccine Safety Datalink (VSD). J Clin Epidemiol. 1998;51:50310. DOIPubMedGoogle Scholar
  111. Andre  FE. Summary of safety and efficacy data on a yeast derived hepatitis B vaccine. Am J Med. 1989;87:14s20s. DOIPubMedGoogle Scholar
  112. Assad  S. Over a decade of experience with a yeast recombinant hepatitis B vaccine. Vaccine. 1999;18:5767. DOIPubMedGoogle Scholar
  113. Revised 2000 National Physician Fee Schedule. Baltimore: Health Care Financing Administration; 2000.
  114. Manton  KG, Etallard  E. Chapter 6: Program payment and utilization trends for Medicare beneficiaries with disabilities. In: Wiener JM, Clauser SB, Kenner DL, editors. Persons with disabilities. Washington: The Brookings Institution; 1995. p. 117-62.
  115. Healthcare Cost and Utilization Project. Nationwide inpatient sample. Rockville (MD): Agency for Healthcare Research and Quality; 1996.
  116. Wholesale acquisition prices for pharmaceuticals in the United States. Montvale (NJ): Medical Economics; 1999.
  117. Gold  M, Franks  P, McCoy  K, Fryback  DG. Toward consistency in cost-utility analyses: using national measures to create condition-specific values. Med Care. 1998;36:77892. DOIPubMedGoogle Scholar
  118. Gage  B, Cardinalli  A, Owens  D. The effect of stroke and stroke prophylaxis with aspirin or warfarin on quality of life. Arch Intern Med. 1996;156:182936. DOIPubMedGoogle Scholar
  119. Lipscomb  J, Weinstein  MC, Torrance  GW. Time Preference. In: Gold MR, Siegel JE, Russell LB, Weinstein MC, editors. Cost-effectiveness in health and medicine. New York: Oxford University Press; 1996. p. 214-35.

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