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Volume 21, Number 10—October 2015
Research

Delayed Disease Progression in Cynomolgus Macaques Infected with Ebola Virus Makona Strain

Andrea Marzi, Friederike Feldmann, Patrick W. Hanley, Dana Scott, Stephan Günther, and Heinz FeldmannComments to Author 
Author affiliations: National Institutes of Health, Hamilton, Montana, USA (A. Marzi, F. Feldmann, P.W. Hanley, D.P. Scott, H. Feldmann); Bernard-Nocht-Institute for Tropical Medicine, Hamburg, Germany (S. Günther)

Main Article

Figure 5

Pathologic results for 6 cynomolgus macaques infected with Ebola virus strains Makona or Mayinga. Liver and spleen sections were stained with hematoxylin and eosin (H & E; top panels) and analyzed for necrosis, microthrombi, lymphocytosis, and inflammation. Sections were also stained with a polyclonal rabbit serum against Ebola virus viral protein 40 for detection of viral antigen (immunohistochemical [IHC] analysis; bottom panels). Sections from a representative animal in each group are sho

Figure 5. Pathologic results for 6 cynomolgus macaques infected with Ebola virus strains Makona or Mayinga. Liver and spleen sections were stained with hematoxylin and eosin (H & E; top panels) and analyzed for necrosis, microthrombi, lymphocytosis, and inflammation. Sections were also stained with a polyclonal rabbit serum against Ebola virus viral protein 40 for detection of viral antigen (immunohistochemical [IHC] analysis; bottom panels). Sections from a representative animal in each group are shown. Original magnification levels: liver, ×40; spleen, ×20.

Main Article

Page created: September 22, 2015
Page updated: September 22, 2015
Page reviewed: September 22, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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