Volume 21, Number 10—October 2015
Letter
Severe Sepsis Caused by California Serogroup Orthobunyavirus
Table
Pathogen testing in patient with undifferentiated severe sepsis, Minnesota, USA, 2014*
Pathogen tested | Serum sample |
|
---|---|---|
Acute phase | Convalescent phase | |
HIV-1/-2 | Ag/Ab screen negative | |
Leptospira | IgM/IgG negative | |
Cryptococcus | Antigen screen negative | |
Anaplasma phagocytophilum | IgG <1:64, PCR negative | |
Ehrlichia chaffeensis | IgG <1:64, PCR negative | |
Ehrlichia ewingii/canis | PCR negative | |
Ehrlichia muris–like | PCR negative | |
Borrelia burgdorferi | Ab screen negative | Ab screen negative |
Babesia microti | IgG <1:64, PCR negative | |
Babesia duncani | PCR negative | |
Babesia divergens strain MO-1 | PCR negative | |
West Nile virus | IgM/IgG and PCR negative | IgM/IgG negative |
Eastern equine encephalitis virus | IgM/IgG <1:10 | IgM/IgG <1:10 |
Western equine encephalitis virus | IgM/IgG <1:10 | IgM/IgG <1:10 |
St. Louis encephalitis virus | IgM/IgG <1:10 | IgM/IgG <1:10 |
California serogroup virus | IgM ≥1:10,† IgG 1:10 | IgM 1:80, IgG 1:320 |
Powassan/tick-borne encephalitis virus‡ | IgM negative | |
La Crosse virus‡ | IgM negative, PRNT <10 | PRNT 320 |
Jamestown Canyon virus‡ | IgM negative, PRNT 160 | PRNT 10,240 |
*Positive control value for PRNT testing was >1,280. Ag, antigen; Ab, antibody, Ig, immunoglobulin, PRNT, plaque reduction neutralization testing.
†Additional dilution of result not performed.
‡Testing performed at the Arboviral Diseases Branch Laboratory, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA.