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Volume 24, Number 10—October 2018
Dispatch

Rapid Spread of Pneumococcal Nonvaccine Serotype 7C Previously Associated with Vaccine Serotype 19F, England and Wales

Ashley MakwanaComments to Author , Shamez N. Ladhani, Georgia Kapatai, Ella Campion, Norman K. Fry, and Carmen Sheppard
Author affiliations: Public Health England’s National Infection Service, London, UK (A. Makwana, S.N. Ladhani, G. Kapatai, E. Campion, N.K. Fry, C. Sheppard); St. George’s University of London, London (S.N. Ladhani)

Main Article

Figure 2

Neighbor-joining tree following single-nucleotide polymorphism analyses on 59 pneumococcal isolates collected in England and Wales during July 2005–June 2017. The percentage of replicate trees in which the associated taxa clustered together in the bootstrap test (1,000 replicates) is shown next to the branch junctions. All positions with <90% site coverage were eliminated. Missing data and ambiguous bases were allowed at any position. There were a total of 20,359 variant positions in the fina

Figure 2. Neighbor-joining tree following single-nucleotide polymorphism analyses on 59 pneumococcal isolates collected in England and Wales during July 2005–June 2017. The percentage of replicate trees in which the associated taxa clustered together in the bootstrap test (1,000 replicates) is shown next to the branch junctions. All positions with <90% site coverage were eliminated. Missing data and ambiguous bases were allowed at any position. There were a total of 20,359 variant positions in the final dataset. Red nodes represent ST177 isolates; green node, an isolate with SLV of ST177; black nodes, non-ST177 isolates. Squares represent 7C serotype; triangles, 24F serotype; and circles 19F serotype. The open circle represents the Taiwan 19F-14 reference sequence (GenBank accession no. NC_012469.1). Scale bar shows the number of nucleotide substitutions represented by branch length. ST, sequence type.

Main Article

Page created: September 16, 2018
Page updated: September 16, 2018
Page reviewed: September 16, 2018
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