Volume 25, Number 5—May 2019
Research Letter
Hepatic Brucelloma Diagnosis and Long-Term Treatment, France
Marie Amsilli
, Olivier Epaulard, Jean-Paul Brion, Patricia Pavese, Christian Letoublon, Isabelle Pelloux, and Max Maurin
, Olivier Epaulard, Jean-Paul Brion, Patricia Pavese, Christian Letoublon, Isabelle Pelloux, and Max Maurin
Table
Diagnostic and blood tests on patient with hepatic brucellosis, Grenoble, France
| Test | Reference value | 2015 Apr | 2015 Nov | 2016 Jan |
|---|---|---|---|---|
| Rose Bengal plate agglutination test (bioMérieux, https://www.biomerieux.com) | NA | Strongly positive | Positive | Negative |
| Tube agglutination test (Elitech, https://www.elitechgroup.com) | >80 | 160 | 20 | <20 |
| Immunofluorescence IgM (BioRad, http://www.bio-rad.com) | >40 | <20 | <20 | <20 |
| Immunofluorescence IgG (BioRad) | >80 | 160 | 160 | 320 |
| Brucella PCR testing of liver tissue biopsies | NA | Positive for 16S rDNA | NA | Positive for bcsp31 gene |
| Blood cultures | NA | Negative | Negative | Negative |
| Liver abscess and tissue cultures† (bacteria, fungi and mycobacteria) | NA | Negative | NA | Negative |
| C-reactive protein, mg/L | <3 | 56 | 5 | 4 |
| Fibrinogen, g/L | 2.1–4.1 | 6.1 | ||
| Leukocyte count, G/L | 4–11 | 8.5 | 5 | 4.9 |
| Neutrophil count, G/L | 1.6–8.8 | 5.9 | 2.5 | 2.1 |
| Thrombocyte count, G/L | 150–400 | 489 | 287 | 284 |
| Bilirubin, µmol/L | 3–17 | 5 | 5 | 5 |
| Alkaline phosphatase, IU/L | 50–136 | 158 | 85 | 69 |
| γ-glutamyl transferase, IU/L | 5–55 | 107 | 31 | 23 |
| Aspartate aminotransferase, IU/L | 15–37 | 20 | 16 | 14 |
| Alanine aminotransferase, IU/L |
12–78 |
28 |
26 |
22 |
| *NA, not applicable. †Tissues were cultured for bacteria, fungi, and mycobacteria. | ||||
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