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Volume 26, Number 8—August 2020
CME ACTIVITY - Research

Sporadic Creutzfeldt-Jakob Disease among Physicians, Germany, 1993–2018

Peter Hermann1Comments to Author , Johannes Treig1, Steffen Unkel, Stefan Goebel, Timothy Bunck, Martha Jünemann, Tim Friede, and Inga Zerr
Author affiliations: University Medical Center Göttingen Department of Neurology, Göttingen, Germany (P. Hermann, J. Treig, S. Goebel, T. Bunck, M. Jünemann, I. Zerr); University Medical Center Göttingen Department of Medical Statistics, Göttingen (S. Unkel, T. Friede); German Center for Neurodegenerative Diseases, Göttingen (I. Zerr)

Main Article

Table 2

Characteristics of physicians with sCJD, Germany, 1993–2018*

Variable Total, N = 22 Surgical, n = 14 Nonsurgical, n = 8
Population-based %†
 100
 39
 61
Sex, no. (%)
F 3 (14) 2 (14) 1 (12)
M
 19 (86)
 12 (86)
 7 (88)
Mean age, y (range)
 67 (53-83)
 65 (53-83)
 69 (60–75)
Classification, no. (%)
Definite 12 (55) 7 (50) 5 (63)
Probable
 10 (45)
 7 (50)
 3 (38)
Mean duration of disease, d (range)§
 175 (49-809)
 205 (84-809)
 109 (49–272)
Codon 129, no.
MM 7 5 2
VV 2 2 0
MV 2 1 1
NA 11 6 5

*MM, methionine homzygosity; MV, heterozygosity; NA, genotype not available; sCJD, sporadic Creutzfeldt-Jakob disease; VV, valine homozygosity.
†Percentage of surgical and nonsurgical specialties among all physicians in 2018 (28).
§Information about disease duration (onset to death) was available for 21 patients,

Main Article

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1These authors contributed equally to this article.

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