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Volume 26, Number 8—August 2020
Research

Human Outbreak of Trichinellosis Caused by Trichinella papuae Nematodes, Central Kampong Thom Province, Cambodia

Yannick CaronComments to Author , Sotharith Bory, Michel Pluot, Mary Nheb, Sarin Chan, Sang Houn Prum, Sun Bun Hong Lim, Mala Sim, Yi Sengdoeurn, Ly Sovann, Virak Khieu, Isabelle Vallée, and Hélène Yera
Author affiliations: Institut Pasteur, Phnom Penh, Cambodia (Y. Caron, M. Sim); Calmette Hospital, Phnom Penh (S. Bory, M. Pluot, M. Nheb, S. Chan); Preah Ket Mealea Hospital, Phnom Penh (S. H. Prum); Kampong Thom Province Hospital, Kampong Thom, Cambodia (S.B.H. Lim); Ministry of Health, Phnom Penh (Y. Sengdoeun, L. Sovann, V. Khieu); Agence Nationale Sécurité Sanitaire Alimentaire Nationale, Maisons-Alfort, France (I. Vallée); Paris University, Paris, France (H. Yera)

Main Article

Table

Characteristics for 25 patients during a human outbreak of trichinellosis caused by Trichinella papuae nematodes, Cambodia*

Pt no. Age, y/sex Clinical signs or symptoms Length of hospital stay, d Leu† Eos† Neu† CPK† LDH† AST† Biopsy result IgM/IgG PCR/PCR/Seq‡
1 26/M Mu, As, Oe, Dy 12 23 3 21 1,210 433 97 + ND –/+/ND
2 31/M Mu, Fe, Hd, Oe, Dy 9 23 4 18 1,216 577 310 + ND –/+/ND
3 20/M Mu, Fe, Cg, Dy 19 28 2 23 784 1,890 89 + ND +/+/+
4 34/M Mu, As, Oe, Dy 14 21 2 19 1,499 469 59 + ND +/+/+
5 25/M Mu, As 4 9 2 4 809 589 74 + ND +/+/+
6 26/M Mu, Fe, Oe 14 20 2 19 340 584 51 + ND +/+/+
7 35/M Mu, Hd, Gi, As, Oe 10 29 3 22 1,265 2,300 104 + ND −/−/ND
8 43/M Mu, Fe, As, Oe 12 15 3 12 1,007 1,940 70 + ND –/+/ND
9 50/M Mu, Oe 7 13 1 10 1,263 830 87 + ND –/+/ND
10 27/M Mu, As, Oe 13 13 3 10 862 592 86 + ND –/+/ND
11 35//M Mu, As, Oe 13 23 3 19 1,367 2,030 115 + ND -/+/ND
12 40/M Mu, Fe, As, Oe, Cg, Dy 15 18 2 16 1,091 536 127 + ND –/+/ND
13 28/F Mu, Fe, Gi, As, Oe, Dy, Cg 18 36 2 35 827 2,540 117 + ND –/+/+
14 46/M Mu, Fe, Gi 17 22 3 20 1,521 248 100 ND –/+ ND
15 22/M Mu, Fe, Hd, As, Gi, Cg 8 16 1 11 110 137 30 ND −/− ND
16 40/M Mu, Fe, Gi, As, Oe 18 18 10 12 1340 342 73 ND ND ND
17 42/M Mu, Fe, Gi, As 16 25 5 20 260 162 44 ND –/+ ND
18 36/M Mu, Fe, Hd, As, Dy 16 17 2 12 899 ND 281 ND –/+ ND
19 42/M Mu, Fe, As 16 24 2 17 796 ND 161 ND +/+ ND
20 26/M Mu, Fe, As 16 21 8 17 340 ND 70 ND +/+ ND
21 26/M Mu, Hd, As Oe 25 18 1 16 1,073 291 94 ND +/+ ND
22 34/M Mu, Fe, As, Dy 25 21 4 20 622 303 89 ND +/+ ND
23 41/M Mu, Fe, Hd, Gi, As 15 16 1 13 866 246 170 ND +/+ ND
24 42/M Mu, Fe, Hd, Gi, As, Dy 15 18 1 15 524 ND 113 ND –/+ ND
25 45/M Mu, Fe, Hd, Gi 7 11 2 15 320 ND 154 ND –/+ ND

*As, asthenia; AST, aspartate aminotransferase (reference range <37 U/L); Cg, cough; CPK, creatine phosphokinase (reference range 15–130 U/L); Dy, dyspnea; Eos, eosinophils (reference range 0.2–0.7 × 109 cells/L); Fe, fever; Gi, abdominal pain, diarrhea, and nausea; Hd, headache; Leu, leukocytes (reference range 4–9 × 109 cells/L); LDH, lactate dehydrogenase (reference range 225–450 U/L); Mu, muscle pain and swelling; ND, not determined; Neu, neutrophils; Oe, facial or periorbital edema; Pt, patient; Seq, sequencing; –, negative; +, positive.
†Values are the highest readings obtained during hospitalization.
‡Positive conventional PCR for Trichinella rDNA intergenic spacer region/multiplex PCR for Trichinella spp./sequencing.

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Page created: May 20, 2020
Page updated: July 17, 2020
Page reviewed: July 17, 2020
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