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Volume 28, Number 3—March 2022
CME ACTIVITY - Research

Neutralizing Enterovirus D68 Antibodies in Children after 2014 Outbreak, Kansas City, Missouri, USA

Robyn A. Livingston1, Christopher J. Harrison1Comments to Author , and Rangaraj Selvarangan1
Author affiliation: Children’s Mercy Hospital Kansas City, Kansas City, Missouri, USA; University of Missouri, Kansas City

Main Article

Table 2

Low versus high neutralizing antibody titers for enterovirus D68 clades B1, B2, and D in serum collected in 2017 compared with titers previously reported from 2012–2013, from patients <18 years of age, Kansas City, Missouri, USA*

Group
 Total
 No. (%) patients
B1 clade virus
 B2 clade virus
 D clade virus
Serum obtained in 2017 300
Low titer† 0 110 (36.7) 66 (22.0)
High titer
300 (100)
 190 (63.3)
 234 (78.0)
Serum obtained in 2012–2013 (18) 273
Low titer† 54 (19.8) 117 (42.9) 133 (48.7)
High titer 219 (80.2) 156 (57.1) 140 (51.3)

*Antibody titers were measured by using the cell viability kit ATPlite (Perkin Elmer, http://www.perkinelmer.com). Seronegative patients are included. †Low neutralizing titer defined as <6 log2 (<1:64 titer).

Main Article

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Main Article

1All authors contributed equally to this article.

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