Volume 29, Number 7—July 2023
Dispatch
Increased Hospitalizations Involving Fungal Infections during COVID-19 Pandemic, United States, January 2020–December 2021
Jeremy A.W. Gold
, Stacey Adjei, Adi V. Gundlapalli, Ya-Lin A. Huang, Tom Chiller, Kaitlin Benedict, and Mitsuru Toda
, Stacey Adjei, Adi V. Gundlapalli, Ya-Lin A. Huang, Tom Chiller, Kaitlin Benedict, and Mitsuru Toda
Table 2
Hospitalizations for fungal infections according to COVID-19 status in study of increased hospitalizations involving fungal infections during COVID-19 pandemic, United States, January 2020–December 2021*
| Fungal pathogen | Any fungal infection | COVID-19–associated | Non–COVID-19–associated | p value |
|---|---|---|---|---|
| Total no. | 39,423 | 5,288 | 34,135 | NA |
| Candida | 8,289 (21.0) | 1,135 (21.5) | 7,154 (21.0) | 0.40 |
| Aspergillus | 7,248 (18.4) | 1,471 (27.8) | 5,777 (16.9) | <0.01 |
| Coccidioides | 6,278 (15.9) | 723 (13.7) | 5,555 (16.3) | <0.01 |
| Pneumocystis | 3,718 (9.4) | 235 (4.4) | 3,483 (10.2) | <0.01 |
| Histoplasma | 2,386 (6.1) | 139 (2.6) | 2,247 (6.6) | <0.01 |
| Cryptococcus | 2,022 (5.1) | 138 (2.6) | 1,884 (5.5) | <0.01 |
| Blastomyces | 543 (1.4) | 41 (0.8) | 502 (1.5) | <0.01 |
| Mucorales species | 569 (1.4) | 94 (1.8) | 475 (1.4) | 0.03 |
| Other specified fungi | 2,300 (5.8) | 221 (4.2) | 2,079 (6.1) | <0.01 |
| Unspecified fungi | 7,599 (19.3) | 1,286 (24.3) | 6,313 (18.5) | <0.01 |
*Values are no. (%) hospitalizations except as indicated. Patients could have >1 fungal infection in a given hospitalization, which occurred for <5% of hospitalizations. p values were calculated by using χ2 tests comparing COVID-19–associated and non–COVID-19–associated fungal hospitalizations. NA, not applicable.
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