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Volume 7, Number 2—April 2001
THEME ISSUE
4th Decennial International Conference on Nosocomial and Healthcare-Associated Infections
State of the Art

Engineering out the Risk of Infection with Urinary Catheters

Dennis G. Maki*Comments to Author  and Paul A. Tambyah†
Author affiliations: *University of Wisconsin Medical School, Madison, Wisconsin, USA; †National University of Singapore Medical School, Singapore

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Table 4

Studies of novel technologies for preventing catheter-associated urinary tract infection

Technologic innovation (refs) Risk reduction in randomized trials
Antiinfective lubricant (2) Unproven
Sealed catheter-collection tubing junctions (38–40) Unproven
Antireflux valves (2) Unproven
Continuous irrigation of bladder with antiinfective solution (2,37) Unproven
Instillation of antiinfective into collection bag (2) Unproven
Antiinfective catheter material
Antimicrobial drug-impregnated
Nitrofurazone (20)
Minocycline-rifampin (21)
Silver oxide (29,30,42)
Silver-hydrogel (22–25,27,42) 0.7 (0.3a)
0.4
Unproven
0.2-0.7

CAUTI = catheter-associated urinary tract infection
aFor bacterial CAUTI.

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