Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 7, Number 5—October 2001

Intraoperative Redosing of Cefazolin and Risk for Surgical Site Infection in Cardiac Surgery

Giorgio Zanetti*†Comments to Author , Richard Giardina*, and Richard Platt*‡
Author affiliations: *Brigham and Women's Hospital, Harvard Medical School, and the CDC Eastern Massachusetts Prevention Epicenter, Boston, Massachusetts, USA; †University Hospital, Lausanne, Switzerland; ‡Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts, USA

Main Article

Table 1

Characteristics of patients undergoing cardiac surgery

Intraoperative antibiotic redosing
Variable Yes (n = 459) No (n = 1,089) p
Mean age (range, years) 65.2 (17-91) 65.7 (20-92) NSa
Mean duration of surgeryb 393 (241-900) 345 (241-700) 0.0001
Male sex (%) 328 (71.5) 744 (68.3) NS
Type of surgery
CABG 317 (69.1) 784 (72.0) NS
Others 142 (30.9) 305 (28.0)
Reoperationc 53 (11.6) 105 (9.6) NS

aNS = not significant; CABG = coronary artery bypass graft.
bMinutes elapsed between administration of preoperative antibiotics and skin closure.
cReoperation within the same hospital stay is included, except for surgery following a diagnosis of surgical site infection.

Main Article

Page created: April 26, 2012
Page updated: April 26, 2012
Page reviewed: April 26, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.