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Volume 7, Number 5—October 2001

Intraoperative Redosing of Cefazolin and Risk for Surgical Site Infection in Cardiac Surgery

Giorgio Zanetti*†Comments to Author , Richard Giardina*, and Richard Platt*‡
Author affiliations: *Brigham and Women's Hospital, Harvard Medical School, and the CDC Eastern Massachusetts Prevention Epicenter, Boston, Massachusetts, USA; †University Hospital, Lausanne, Switzerland; ‡Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts, USA

Main Article

Table 2

Independent predictors of surgical site infections after cardiac surgery

Predictor Adjusted odds ratio for SSIa 95% confidence interval pb
Procedures lasting <400 min
Agec 1.2 1.00-1.45 0.049
CABG surgery 1.84 1.05-3.20 0.032
Duration of surgeryd 1.38 1.00-1.82 0.032
Intraoperative redosing of antibiotics 1.27 0.80-2.02 0.319
Procedures lasting >400 min
CABG surgery 2.2 1.05-4.61 0.036
Intraoperative redosing of antibiotics 0.44 0.23-0.86 0.016

aSSI: surgical site infection; CABG: coronary artery bypass graft.
bWald test.
cOdds ratio for every additional decade of age.
dOdds ratio for every additional hour of surgery.

Main Article

Page created: April 26, 2012
Page updated: April 26, 2012
Page reviewed: April 26, 2012
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