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Volume 8, Number 12—December 2002

Legionnaires’ Disease at a Dutch Flower Show: Prognostic Factors and Impact of Therapy

Kamilla D. Lettinga*Comments to Author , Annelies Verbon*, Gerrit-Jan Weverling*, Joop F.P. Schellekens†, Jeroen W. Den Boer†‡, Ed P.F. Yzerman§, Jacobus Prins¶, Wim G. Boersma#, Ruud J. van Ketel*, Jan M. Prins*, and Peter Speelman*
Author affiliations: *Academic Medical Center, Amsterdam, the Netherlands; †National Institute of Public Health and the Environment, Bilthoven, the Netherlands; ‡Municipal Health Service Zuid-Kennemerland, Haarlem, the Netherlands; §Regional Laboratory of Public Health Haarlem, Haarlem, the Netherlands; ¶Westfries Gasthuis, Hoorn, the Netherlands; #Medical Center Alkmaar, Alkmaar, the Netherlands;

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Table 3

Positive results of other diagnostic tests of patients with positive and negative urinary antigen testsa

Diagnostic test Positive urinary antigen testb (n=86) Negative urinary antigen test (n=51)
Sputum culture 23 3
Fourfold rise in titer/seroconversion 35 27
Polymerase chain reaction 9 1
Single high titer 5 3
Positive urinary antigen ELISAb test in concentrated urinec NA 7
No positive test results 29 17

aNA, not applicable; ELISA, enzyme-linked immunosorbent assay.
bUrinary antigen test results were based on the test result of the qualitative immunochromatographic assay (Binax Now, Binax, Portland, ME).
cPositive Binax EIA and Biotest EIA in concentrated urine samples.

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