Volume 8, Number 12—December 2002
Research
Efficacy of Killed Virus Vaccine, Live Attenuated Chimeric Virus Vaccine, and Passive Immunization for Prevention of West Nile virus Encephalitis in Hamster Model
Table 6
WNV hemagglutination inhibition antibody titers in adult hamsters 24 h after inoculation (passive immunization) with WNV immune serum, and 7 days later after challenge with WNV (104.0 TCID50 given intraperitoneally)a
Hamster no. | 24 h after passive immunization | 7 days after challenge with WNV |
---|---|---|
Group A – received 0.5 mL WNV immune serum | ||
H-8126 | 1:40b | 0 |
H-8127 | 1:20 | 0 |
H-8128 | 1:20 | 0 |
H-8129 | 1:20 | 0 |
H-8130 | 1:20 | 0 |
H-8138 | 1:40 | 0 |
H-8139 | 1:40 | 1:10 |
Group B – received 0.1 mL WNV immune serum) | ||
H-8131 | 0 | 0 |
H-8132 | 0 | 0 |
H-8133 | 0 | 0 |
H-8134 | 0 | 0 |
H-8135 | 0 | 0 |
H-8136 | 0 | 0 |
H-8137 | 0 | 0 |
aWNV, West Nile virus.
bHemagglutination inhibition antibody titer. 0 = <1:10.