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Volume 12, Number 9—September 2006

Genomic Signatures of Human versus Avian Influenza A Viruses

Guang-Wu Chen*1, Shih-Cheng Chang*1, Chee-Keng Mok*, Yu-Luan Lo*, Yu-Nong Kung*, Ji-Hung Huang*, Yun-Han Shih*, Ji-Yi Wang*, Chiayn Chiang*, Chi-Jene Chen*, and Shin-Ru Shih*Comments to Author 
Author affiliations: *Chang Gung University, Taoyuan, Taiwan, Republic of China

Main Article

Table 2

Summary of host-associated amino acid signature changes

Gene Position Residue* H5N1 H9N2 H7N2 H7N7
PB2 199 A(19) 15 3 1
S(5) 5
271 T(23) 20 2 1
A(1) 1
627 E(22) 19 3
K(7) 6 1
PB1-F2 73 K(24) 17 2 5
R(2) 2
79 R(24) 17 2 5
Q(2) 2
82 L(21) 19 2
S(5) 5
PA 409 S(17) 12 3 2
N(7) 7
M2 20 S(34) 31 2 1
N(5) 5
NS2 70 S(26) 22 2 2
G(1) 1

*Top half displays an avian-specific residue with the count in parentheses and distribution among subtypes, and the bottom half represents a human-specific residue.

Main Article

1These authors contributed equally to this article.

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