Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 27, Number 2—February 2021
Research

Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions in Strains from Nigeria, Sudan, and South Sudan

Christiane ProsserComments to Author , Karryn Gresty, John Ellis, Wieland Meyer, Karen Anderson, Rogan Lee, and Qin Cheng
Author affiliations: Australian Defence Force Malaria and Infectious Disease Institute, Brisbane, Queensland, Australia (C. Prosser, K. Gresty, K. Anderson, Q. Cheng); Westmead Institute for Medical Research, Westmead, New South Wales, Australia (C. Prosser, W. Meyer); University of Sydney, Sydney, New South Wales, Australia (C. Prosser, W. Meyer, R. Lee); QIMR–Berghofer Medical Research Institute, Brisbane (K. Gresty, K. Anderson, Q. Cheng); University of Technology Sydney, Sydney (J. Ellis); Westmead Hospital, Westmead (W. Meyer); Marie Bashir Institute for Infectious Diseases and Biosecurity, University of Sydney, Sydney (W. Meyer); Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR, Westmead Hospital, Westmead (R. Lee)

Main Article

Table 1

Summary of pfhrp2/pfhrp3 gene deletion screening results showing pfhrp2/pfhrp3 status for Plasmodium spp. isolates, by parasite country of origin, Australia*

Source Country/strain name No. cases pfhrp2/pfhrp3 status, no. (%)
 % Symptomatic % Refugee
+/− −/+ −/−
Africa Cameroon 3 0 0 0 66.6 33.3
Gambia 5 0 0 0 100 0
Ghana 17 0 1 (0.06) 0 100 0
Ivory Coast 2 0 0 0 100 0
Kenya 18 0 1 (0.06) 0 100 0
Madagascar 1 0 0 0 100 0
Malawi 6 0 0 0 33.3 66.6
Mali 3 0 1 (33.3) 0 100 0
Nigeria 30 0 4 (13.3) 0 100 0
Sierra Leone 13 0 0 0 92.3 7.7
South Africa 2 0 0 0 100 0
South Sudan 17 1 (5.9) 3 (17.6) 0 52.9 47.1
Sudan 39 1 (2.6) 4 (10.3) 0 100 0
Sumatra 2 1 (50) 0 0 100 0
Togo 1 0 1 (100) 0 100 0
Tanzania 4 1 (25) 0 0 100 0
Uganda 2 0 0 0 100 0
Zambia 5 0 1 (20) 0 100 0
Zimbabwe 1 0 0 0 100 0
Unknown†
 27
 0
 3 (11.1)
 0
 100
 0
Asia Cambodia 1 0 0 0 100 0
India 3 0 0 0 100 0
Indonesia 1 0 0 0 100 0
Papua New Guinea 5 0 0 0 100 0
Thailand
 1
 0
 0
 0
 100
 0
South America
 Peru
 1
 1 (100)
 0
 0
 100
 0
Laboratory strains 3D7 1 0 0 0 NA NA
3BD5 1 0 0 1 (100) NA NA
D10 1 0 1 (100) 0 NA NA
Dd2 1 0 1 (100) 0 NA NA
HB3 1 0 1 (100) 0 NA NA

*NA, not applicable.
†Cases in which clinical notes state African origins but do not specify a country.

Main Article

Page created: December 22, 2020
Page updated: January 23, 2021
Page reviewed: January 23, 2021
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external