Volume 10, Number 11—November 2004
Research
Topographic Changes in SARS Coronavirus–infected Cells during Late Stages of Infection
Figure 6

Figure 6. Atomic force microscopy of Vero cells infected with severe acute respiratory syndrome–associated coronavirus. A) High activity of virus extrusion at the thickened edge of the infected cells (arrow). Arrowheads indicate virus particles. B) A three-dimensional reconstruction of the image in panel A shows the puffy edge of infected cells. Many intracellular viruses are visible just under the plasma membrane (arrows). Extruded virus particles are present on other areas of the cell surface (arrowheads).