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Volume 28, Number 9—September 2022

Detection of Endosymbiont Candidatus Midichloria mitochondrii and Tickborne Pathogens in Humans Exposed to Tick Bites, Italy

Giovanni Sgroi1, Roberta Iatta1, Piero Lovreglio, Angela Stufano, Younes Laidoudi, Jairo Alfonso Mendoza-Roldan, Marcos Antonio Bezerra-Santos, Vincenzo Veneziano, Francesco Di Gennaro, Annalisa Saracino, Maria Chironna, Claudio Bandi, and Domenico OtrantoComments to Author 
Author affiliations: University of Bari Aldo Moro, Bari, Italy (G. Sgroi, R. Iatta, P. Lovreglio, A. Stufano, Y. Laidoudi, J.A. Mendoza-Roldan, M.A. Bezerra-Santos, F. Di Gennaro, A. Saracino, M. Chironna, D. Otranto); University of Naples Federico II, Naples, Italy (V. Veneziano); Osservatorio Faunistico Venatorio, Naples (V. Veneziano); University of Milan Statale, Milan, Italy (C. Bandi); Bu-Ali Sina University, Hamedan, Iran (D. Otranto)

Main Article

Table 2

Serologic and PCR findings for tickborne pathogens in humans exposed to tick bites, Italy, 2021*

Tickborne pathogens Serology
No. patients % Patients (95% CI)† No. patients (%) % Patients (95% CI)†
Single infections
Coxiella burnetii 21 15.6 (10.4–22.6) 7 5.2 (2.5–10.3)
Rickettsia raoultii 14 10.4 (6.3–16.7) 6 4.4 (2.0–9.4)
Borrelia lusitaniae
5 (1.6–8.4)

4.4 (2.0–9.4)
Coxiella burnetii, Rickettsia spp. 11 11 (4.6–14.0) NA NA
Coxiella burnetii, Borrelia spp. 2 2 (0.4–5.2) NA NA
Rickettsia raoultii, Borrelia lusitaniae
1 (0.1–4.1)

0.7 (0.1–4.1)
Total 54 54 (32.1–48.4) 20 14.8 (9.8–21.8)

*Based on 135 persons tested. NA, not applicable †Exact binomial 95% CI.

Main Article

1These authors contributed equally to this article.

Page created: July 27, 2022
Page updated: August 19, 2022
Page reviewed: August 19, 2022
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